Boosting Immune Memory for Enhanced Cancer Therapy
Reductive carboxylation epigenetically instructs T cell differentiation Immune cells called CD8+ T cells play a crucial role in protecting the body from diseases like cancer by undergoing metabolic changes when activated. Researchers found that one specific metabolic process involving a mitochondrial enzyme called IDH2 affects the development of memory CD8+ T cells. Inhibiting IDH2 during…
