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Study on Dexamethasone for Tuberculous Meningitis in HIV Patients

ByThe Short Paper

This was a double-blind, randomized trial involving HIV-positive adults with tuberculous meningitis in Vietnam and Indonesia examined the effectiveness of dexamethasone, an anti-inflammatory drug, as an adjunct treatment. Participants received either dexamethasone or a placebo in addition to antituberculosis therapy. The study found that dexamethasone did not significantly improve survival rates or secondary outcomes, such…

Mezigdomide plus Dexamethasone in Relapsed and Refractory Multiple Myeloma

ByThe Short Paper

This study tested a new treatment called mezigdomide, combined with dexamethasone, for people with multiple myeloma (a type of cancer). The treatment showed promise in patients who had already tried other treatments, including those resistant to lenalidomide and pomalidomide. In the first phase of the study, they tested the treatment on 77 patients to determine…