Global health burden and cost of lead exposure in children and adults: a health impact and economic modelling analysis Despite significant reductions in lead exposure, it remains a global health threat. A recent study estimated the worldwide burden and cost of intelligence quotient (IQ) loss and cardiovascular disease mortality due to lead exposure. Findings revealed…
CAR T-cell therapy in autoimmune diseases For patients not responding to current autoimmune disease treatments, a promising approach involves using engineered T cells (CAR T cells) that target autoreactive B cells, which are responsible for diseases like lupus and arthritis. Recent studies using CD19 CAR T cells have shown rapid and sustained depletion of B…
Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial Efgartigimod, a novel therapy for primary immune thrombocytopenia (ITP), has shown significant efficacy in a phase 3 study. ITP, an autoimmune disorder causing low platelet counts and bleeding, was treated…
