Effectiveness of Remote Ischemic Conditioning for Acute Stroke

Remote Ischemic Conditioning for Acute Stroke: The RESIST Randomized Clinical Trial

This study evaluated remote ischemic conditioning (RIC), a treatment involving cycles of limb ischemia and reperfusion, for acute stroke. Despite promising earlier data, the study found that RIC, when started in ambulances and continued in hospitals, did not significantly improve functional outcomes at 90 days for patients with acute stroke compared to sham treatment.

Blauenfeldt RA, Hjort N, Valentin JB, et al. Remote Ischemic Conditioning for Acute Stroke: The RESIST Randomized Clinical Trial. JAMA. 2023;330(13):1236–1246. doi:10.1001/jama.2023.16893


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