Link to the article: https://www.nejm.org/doi/full/10.1056/NEJMra1905136
This is a review paper where they reviewed the available literature concerning intermittent fasting. Going straight to the conclusion, preclinical and clinical trials show positive effects on patients, specifically those with obesity, diabetes, cancer, cardiovascular disease, and neurologic disorder. Animal models have shown to have positive results involving their health. Most studies in humans are limited to overweight young and middle-age adults and so they can not conclude benefits outside this group. The mechanism is not quite fully understood, but possible pharmaceutical drugs may be produced to mimic the effect. However, the effect might be limited based on animal models.