Simple Summary – Physiological Responses to Maximal Eating in Men

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32248846/ The study looked at 14 men with average body mass where they would have an occasion to eat comfortably and the other occasion to eat until maximal fullness. Both times they were eating pizza. They found that if you ate until maximal fullness, they could eat double the calories as the…

Simple Summary – The Longitudinal Relationship Between Dietary Intake, Physical Activity and Muscle Strength Among Adolescents

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32624008/ The study looked at 436 adolescents starting at age 13 and followed up at ages 15 and 17. They studied the relationship between dietary intake, physical activity, and muscle strength. They found an increase in strength for male adolescents correlating with protein and carbohydrate consumption over the course of five years….

Simple Summary – Association of Egg Intake With Blood Lipids, Cardiovascular Disease, and Mortality in 177,000 People in 50 Countries

Link to the article: https://pubmed.ncbi.nlm.nih.gov/31965140/ The study looked at 146,011 people from 21 countries. Egg consumption was recorded using food frequency questionaire. They looked a the hazard ratios of those people and found no association with egg consumption and blood lipids, mortality, or major cardiovascular events. TL;DR Eggs aren’t associated with increased health complications (CVD, blood…

Simple Summary – Intermittent Fasting, Paleolithic, or Mediterranean Diets in the Real World: Exploratory Secondary Analyses of a Weight-Loss Trial That Included Choice of Diet and Exercise

Link to the article: https://pubmed.ncbi.nlm.nih.gov/31879752/ Intermittent fasting (IF) and Paleolithic (Paleo) have been studied before and found to be effective in controlled studies. The study gave 250 overweight patients the option of Mediterranean, IF, or Paleo diets. Most chose IF. Many patients did not stick to their diet over the course of a year. On average…

Simple Summary – Risk Factors for Mortality in Patients With COVID-19 in New York City

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32607928/ This was a retrospective study taking place in New York City looking at 6,493 patients positive for COVID-19. They looked at specific vital signs and laboratory values and found low blood pressure, increased heart rate, low oxygen, kidney function, and increased D-dimer had increased hazard ratios. Being female, African-American, and hydroxychloroquine…

Simple Summary – COVID-19 in Children and Adolescents in Europe: A Multinational, Multicentre Cohort Study

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32593339/ This a Europe based study where pediatric data was gathered across 25 different countries. Using PCR, they identified 582 children with COVID-19 of which they found that a large majority had mild disease. However, 4% were symptomatic and 0.69% died. TL;DR COVID-19 is a mild in children but a small part…

Simple Summary – COVID-19 Fatalities, Latitude, Sunlight, and Vitamin D

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32599103/ Vitamin D has been found to be important for the immune system and typically equator countries tend to have a higher dose due to their location. Looking at 88 countries and available data, they found there was a relationship between latitude and COVID-19 deaths consistent with previous literature. Populations at risk…

Simple Summary – Antibody Tests for Identification of Current and Past Infection With SARS-CoV-2

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32584464/ They reviewed 57 papers looking at the sensitivity and specificity of their testing. They found that testing was useful early on but was useful after >15 days. After 35 days, data is limited and so using it determine prevalence in the general population is limited. Data available is limited and selective…

Simple Summary – MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma

Link to the article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302353/ MicroRNA can have suppressive effects on certain biochemical pathways involved in cancer specifically osteosarcoma in regards to this paper. Using bioinformatics techniques, they were able to hone into specific miRNA that can suppress osteosarcoma. TL;DR Increases in certain molecular mechanisms can help suppress bone cancer (osteosarcoma)

Simple Summarize – Increased body mass index percentile is associated with decreased epiphyseal tubercle size in asymptomatic children and adolescents with healthy hips

Link to the article: https://pubmed.ncbi.nlm.nih.gov/32582383/ This article talks about slipped capital femoral epiphysis (SCFE) and the possible causes of it. One of which is a high BMI. They looked at 68 healthy hips/subjects. They found there was a correlation between BMI percentile and decreased epiphyseal tubercle size which is a factor contributing to reduced epiphyseal stability. TL;DR…