Link to the paper: https://www.nejm.org/doi/full/10.1056/NEJMoa1900105 The World Health Organization, WHO, has specific guidelines for transfusion in African countries due to the scarcity of blood products. Patients with extreme anemia do not necessarily receive transfusion unless fitting specific guidelines. The WHO guideline cutoff values are substantially less than values used in other areas of the world. This…

Link to the paper: https://www.ncbi.nlm.nih.gov/pubmed/31367040 Systemic inflammation from cancer is linked to a poor outcome for cancer patients. Inflammation is a biochemical response in the body where white blood cells and other cells secrete substances to protect the body from infections, diseases, and injuries. However, this does not always necessarily turn out well for the…

Link to the paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206485/ HIV viruses are difficult to treat partly due to their ability to mutate. This makes it difficult for scientists and your body to target and destroy viruses. With the advent of DNA vaccines, it gives us another way we can possibly target HIV viruses. What are DNA vaccines? DNA vaccines are a…

Link to the paper: https://www.ncbi.nlm.nih.gov/pubmed/22914710 Introduction It’s been found that the usage of allogenic blood products are independently associated with increased mortality and adverse events. In literature, it states that an accurate diagnosis of underlying hemostatic pathology is important and so having an algorithm driven hemostatic therapy is important and found to be better than clinical…