Mezigdomide plus Dexamethasone in Relapsed and Refractory Multiple Myeloma

This study tested a new treatment called mezigdomide, combined with dexamethasone, for people with multiple myeloma (a type of cancer). The treatment showed promise in patients who had already tried other treatments, including those resistant to lenalidomide and pomalidomide. In the first phase of the study, they tested the treatment on 77 patients to determine…

Antibiotic Prophylaxis in Infants with Grade III, IV, or V Vesicoureteral Reflux

This study looked at the use of continuous antibiotic treatment to prevent urinary tract infections (UTIs) in infants with severe vesicoureteral reflux (a condition where urine flows back from the bladder to the kidneys). The study involved infants aged 1 to 5 months who had not had a UTI before. The results showed that those…

Ferric Carboxymaltose in Heart Failure with Iron Deficiency

This study looked at a treatment called ferric carboxymaltose for people with heart failure who also had low iron levels. They compared it to a placebo (a fake treatment) alongside standard heart failure therapy. The study involved over 3,000 patients. The results showed that there wasn’t a significant difference between the two groups in terms…

Early-childhood linear growth faltering in low- and middle-income countries

Around the world, about 149 million children under 5 years old are too short for their age, which can lead to health problems and even death. Current estimates rely on surveys that don’t tell us when this growth problem starts or if it gets better. This study looked at data from many countries and found…

Projected decline in European bumblebee populations in the twenty-first century

Bumblebee populations in Europe are expected to decrease in the 21st century Habitat damage and climate change are causing a major decline in wildlife worldwide, and this trend is expected to get worse in the coming decades. This study focuses on bumblebees, crucial pollinators for crops in Europe. They found that bumblebee populations have been…

DNA-based programmable gate arrays for general-purpose DNA computing

In recent years, electronic and photonic circuits have become more versatile, going from specialized to programmable. Now, researchers have developed a system called DNA Integrated Circuits (DICs) using DNA molecules. These DICs can be programmed for various computing tasks and have the potential for massive parallel processing. The researchers used specific DNA strands as a…

Child wasting and concurrent stunting in low- and middle-income countries

The goal is to end child malnutrition by 2030, which includes tackling “child wasting,” where kids are too thin for their height. Traditional methods for measuring this problem only give a snapshot, missing when it starts and ends. This study looked at data from 21 groups of children and found that child wasting is a…

Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir

Nirmatrelvir is a medication used to treat COVID-19. However, researchers were previously uncertain about how the virus could develop resistance to it. Recent findings have revealed that the virus can undergo two distinct changes to resist the medication. Some of these changes hinder the medicine’s effectiveness, while others make the virus more resilient. These combined…

Food Insecurity Is Associated With Higher Health Care Use And Costs Among Canadian Adults

Article The researchers looked at Canadian hospital and healthcare expenditure records. They looked at specific characteristics of patients specifically acute care hospitalization, same-day surgery, and acute care costs among Canadian adults. Patients who were more food insecure were more likely to be admitted for acute care as well as having surgery. They  found that patients…

Evaluating Coca-Cola’s attempts to influence public health ‘in their own words’: analysis of Coca-Cola emails with public health academics leading the Global Energy Balance Network

Article Using the Freedom of Information Act, researchers were able to obtain 18,030 pages of emails between Coca-Cola and West Virginia University and University of Colorado. The company attempted to fund research through various methods to obscure their relationship to the funding; even withholding information that Coca-Cola was behind the funding.  Researchers also found documentation of pushing…