Remote Ischemic Conditioning for Acute Stroke: The RESIST Randomized Clinical Trial This study evaluated remote ischemic conditioning (RIC), a treatment involving cycles of limb ischemia and reperfusion, for acute stroke. Despite promising earlier data, the study found that RIC, when started in ambulances and continued in hospitals, did not significantly improve functional outcomes at 90…
CAR T-cell therapy in autoimmune diseases For patients not responding to current autoimmune disease treatments, a promising approach involves using engineered T cells (CAR T cells) that target autoreactive B cells, which are responsible for diseases like lupus and arthritis. Recent studies using CD19 CAR T cells have shown rapid and sustained depletion of B…
Medical journals have been using visual abstracts (VAs) since 2016 to promote research on social media. This study assessed the impact of different types of VAs on social media engagement across various journals within the JAMA Network. Linking VAs, which directly open the article, received more clicks, while expandable VAs, which enlarge when clicked, garnered…
Protected areas slow declines unevenly across the tetrapod tree of life Protected areas (PAs) play a crucial role in slowing down the loss of terrestrial biodiversity. A study analyzing data from around the world found that vertebrate populations decline much slower within protected areas compared to similar sites without protection. The effectiveness of PAs varied…
Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial Efgartigimod, a novel therapy for primary immune thrombocytopenia (ITP), has shown significant efficacy in a phase 3 study. ITP, an autoimmune disorder causing low platelet counts and bleeding, was treated…
The geography of climate and the global patterns of species diversity Traditionally, climate’s impact on global biodiversity was understood in terms of temperature and humidity. However, a new study shifts this perspective, considering the size and fragmentation of climate regions. The research shows that larger and more isolated climate regions support higher biodiversity among terrestrial…
The use of unclaimed bodies in US medical education, although declining, still occurs without consent from the deceased or their next of kin. This study aims to investigate the trends of unclaimed body usage in medical education specifically in Texas, shedding light on this underresearched practice. Shupe E, Karim S, Sledge D. Unclaimed Bodies and Medical Education…
Precessing jet nozzle connecting to a spinning black hole in M87 Scientists have studied the radio galaxy M87, providing insights into the intricate relationship between supermassive black holes and their relativistic jets. M87’s active galactic nucleus (AGN), a compact, energetic region at the galaxy’s core, emits various forms of radiation beyond what stars produce. The…
Seasonal advance of intense tropical cyclones in a warming climate Intense tropical cyclones (TCs) occurring in autumn are shifting earlier in the season, with rates of 3.7 and 3.2 days per decade in the Northern and Southern Hemispheres. This shift is linked to favorable oceanic conditions starting earlier, driven primarily by greenhouse gas forcing. As…
Observation of the effect of gravity on the motion of antimatter Einstein’s general theory of relativity, which describes gravity, has been highly successful in experimental tests. However, concepts like dark matter and dark energy suggest gaps in our understanding of the universe’s gravitational properties. Researchers are exploring gravity in unique settings, including with antimatter. A…
