|

Understanding the Link Between Brain Activity and Cancer Growth

ByThe Short Paper

Glioma synapses recruit mechanisms of adaptive plasticity

Research reveals that the nervous system plays a significant role in cancer regulation, particularly in gliomas, a type of brain cancer. Neuronal activity influences tumor progression through specific signaling factors. In gliomas, the brain-derived neurotrophic factor (BDNF) promotes synaptic plasticity, similar to healthy brain functions. Malignant synapses in cancer cells exhibit plasticity regulated by BDNF, promoting tumor growth. Blocking BDNF-related pathways inhibits glioma progression, highlighting the connection between neural activity, synaptic strength, and cancer advancement.

Taylor, K.R., Barron, T., Hui, A. et al. Glioma synapses recruit mechanisms of adaptive plasticity. Nature (2023). https://doi.org/10.1038/s41586-023-06678-1

https://www.nature.com/articles/s41586-023-06678-1

Similar Posts

|

Assessing Health Impacts of Canadian Wildfires on New York City: Asthma and Air Quality

ByThe Short Paper

Canadian Wildfire Smoke and Asthma Syndrome Emergency Department Visits in New York City In 2023, wildfires in Canada not only impacted air quality locally but also had effects hundreds of kilometers away, such as in New York City (NYC), where they caused increased levels of fine particulate matter (PM2.5) known to affect health. While previous…

|

Surprising Discoveries About Responsiveness During Sleep

ByThe Short Paper

Behavioral and brain responses to verbal stimuli reveal transient periods of cognitive integration of the external world during sleep For a long time, it was believed that sleep was a state of complete disconnection from the outside world, where individuals were unresponsive to external stimuli. However, a study challenged this idea by examining how people…

|

Inhaled Amikacin Reduces Ventilator-Associated Pneumonia in Critically Ill Patients

ByThe Short Paper

Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia This clinical trial investigated whether inhaled amikacin, an antibiotic, could reduce the incidence of ventilator-associated pneumonia in critically ill patients on mechanical ventilation for at least 3 days. The study included 847 patients who received either inhaled amikacin or a placebo for 3 days. Results showed that inhaled amikacin…

|

Uncovering the Biology of Long COVID

ByThe Short Paper

Distinguishing features of Long COVID identified through immune profiling Some people develop post-acute infection syndromes (PAIS) after recovering from viral diseases like COVID-19, resulting in symptoms known as “Long COVID” (LC), including fatigue and cognitive issues. A study involving 273 individuals, some with LC and some without, used immune profiling and machine learning to identify…

|

Socioeconomic Status Influences Medical School Acceptance Rates, Study Finds

ByThe Short Paper

Temporal Trends in Childhood Household Income Among Applicants and Matriculants to Medical School and the Likelihood of Acceptance by Income, 2014-2019 This study analyzed data on applicants and matriculants to US medical school programs between 2014 and 2019 to investigate trends in childhood household income among medical school applicants and its influence on acceptance rates….

|

Promising Breakthrough for Efgartigimod Efficacy in Chronic Immune Thrombocytopenia

ByThe Short Paper

Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial Efgartigimod, a novel therapy for primary immune thrombocytopenia (ITP), has shown significant efficacy in a phase 3 study. ITP, an autoimmune disorder causing low platelet counts and bleeding, was treated…