|

Understanding the Link Between Brain Activity and Cancer Growth

ByThe Short Paper

Glioma synapses recruit mechanisms of adaptive plasticity

Research reveals that the nervous system plays a significant role in cancer regulation, particularly in gliomas, a type of brain cancer. Neuronal activity influences tumor progression through specific signaling factors. In gliomas, the brain-derived neurotrophic factor (BDNF) promotes synaptic plasticity, similar to healthy brain functions. Malignant synapses in cancer cells exhibit plasticity regulated by BDNF, promoting tumor growth. Blocking BDNF-related pathways inhibits glioma progression, highlighting the connection between neural activity, synaptic strength, and cancer advancement.

Taylor, K.R., Barron, T., Hui, A. et al. Glioma synapses recruit mechanisms of adaptive plasticity. Nature (2023). https://doi.org/10.1038/s41586-023-06678-1

https://www.nature.com/articles/s41586-023-06678-1

Similar Posts

|

Simvastatin’s Efficacy in Treating Critically Ill COVID-19 Patientsc

ByThe Short Paper

Simvastatin in Critically Ill Patients with Covid-19 This study evaluated the effectiveness of simvastatin (a cholesterol-lowering medication) in treating critically ill COVID-19 patients. The trial involved 2684 patients and aimed to determine if simvastatin could increase the number of days free from respiratory and cardiovascular support. The results showed that simvastatin did not meet the…

|

Gut Fungi and Immune Activation in Severe COVID-19: New Insights

ByThe Short Paper

Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 This study delves into the role of gastrointestinal fungal dysbiosis in severe COVID-19 cases and its impact on the host’s immune system. Elevated levels of Candida albicans antibodies were found in severe COVID-19 patients with gut Candida overgrowth, mycobiota imbalance, and…

|

Suicide Risk Among US Healthcare Workers

ByThe Short Paper

Suicide Risks of Health Care Workers in the US This study aimed to estimate the risk of suicide among different groups of healthcare workers in the US. They analyzed data from a large sample of healthcare professionals and found that registered nurses, health technicians, and health care support workers had a higher risk of suicide…

|

Rapid Expansion of Human Settlements into Flood Zones Increases Disaster Vulnerability

ByThe Short Paper

Global evidence of rapid urban growth in flood zones since 1985 This study reveals that human settlements worldwide, from small villages to large cities, have been rapidly expanding into areas prone to flooding since 1985. This expansion is happening more quickly in high-risk flood zones compared to safer areas, particularly in East Asia. These findings…

|

Worldwide ICU Blood Transfusion Practices Study

ByThe Short Paper

Red Blood Cell Transfusion in the Intensive Care Unit A global study conducted in 30 countries on six continents between March 2019 and October 2022 evaluated and described red blood cell (RBC) transfusion practices in 233 intensive care units (ICUs). Among 3,643 adult patients, 25% received one or more RBC transfusions during their ICU stay,…

|

Global Study Reveals Impact of Modifiable Risk Factors on Cardiovascular Health and Mortality

ByThe Short Paper

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality A global study analyzed data from over 1.5 million participants to assess the impact of five modifiable risk factors (body-mass index, blood pressure, cholesterol levels, smoking, and diabetes) on cardiovascular disease and overall mortality. The research found that these risk factors are associated with…